In mid-2024, the Research.com Medicine platform published a ranking of the world's leading scientists based on the citation rate of their publications in various databases, including OpenAlex and CrossRef. The criteria for including scientists in the ranking were the value of the so-called D-index (disciplinary Hirsch index), which takes into account the volume of the publication portfolio and citation indicators in a particular field, as well as the awards and achievements of researchers. The established threshold of the D-index guaranteed the possibility of identifying a cluster of "1% of the world's leading scientists" in each subject area. In the field of medicine, the status of the world's leading scientist was received by David Georgievich Zaridze, oncologist-epidemiologist, professor, Corresponding Member of the Russian Academy of Sciences, President of the Anti-Cancer Society of Russia, Head of the Department of Clinical Epidemiology of the Research Institute of Clinical Oncology Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology".

   Introduction. The increase in the number of diseases associated with malnutrition has reached global proportions and has become a serious problem for health systems around the world. For example, in the United States, about 36 % of the adult population is obese, in Russia, Georgia and the Republic of Belarus this figure ranges from 21% to 24%. Foreign experience (the Netherlands and the USA) illustrates that the population’s idea of proper nutrition is unrealistic: underestimation of high fat intake, low consumption of vegetables and fruits, etc., relative to their daily allowance, misconception in assessing the balance of their own diet, etc.

   The purpose of the study: to study the commitment of the population to proper nutrition and to determine the factors influencing people’s choice.

   Materials and methods. In this work, a questionnaire method was used using a developed questionnaire consisting of seven blocks and 46 questions. Statistical analysis of the data was carried out using the programs Statistica for Windows version 10.0 and R-studio.

   Results. 2,731 respondents over the age of 18 (45.7 % men and 54.3 % women) from all regions of the Russian Federation took part in the survey. Only 5 % (n = 136) replied that they constantly adhered to proper nutrition, a large proportion preferred not to do it at all (43.4 %, n = 1,186) and a third – from time to time (37.3 %, n = 1,018). In addition, it is important that 14.3 % of respondents (n = 391) found it difficult to answer the question, which is most likely due to a lack of understanding of what the concept of «proper nutrition» includes. The parameters related to the observance of proper nutrition by the respondents were female gender, high financial status and regular breakfast intake. In addition, non-smokers, as well as people who, when choosing food in the store, paid attention to the composition, calorie content and the inscription «GMO-free»/ «Sugar-free»/ «Healthy food», had a higher chance of adhering to a proper diet compared to the rest of the participants.

   Conclusion. It is necessary to increase the commitment and awareness of the population about proper nutrition, focusing primarily on men, obese people, low financial status, workers/employees/specialists, smokers, who often ate at night, ate semi-finished products at home, and ate everything that was on the plate to the end.

   Introduction. The growing prevalence of obesity in the world and the accumulated scientific data and practical knowledge have prompted the World Health Organization to declare obesity a global pandemic and a worldwide public health crisis. According to research, in 2015, 603.7 million adults and 107.7 million children worldwide were obese, and the overall prevalence of obesity was 12.0 and 5.0 %, respectively, while overweight caused 4.0 million deaths and 120 million lost years of life.

   The purpose of the study: to assess trends and age and sex structure of obesity prevalence in Russia according to different sources.

   Materials and methods. We calculated the prevalence of obesity using data from Rosstat (2018–2023) and the Russia Longitudinal Monitoring Survey (1994–2022), as well as the structure of obesity by sex and age groups in dynamics, and the structure of obesity by degree (2022).

   Results. According to the results of calculations based on Rosstat data, the prevalence of obesity among men increased from 17.8 % in 2018 to 20.9 % in 2023, and among women from 24.5 % to 28.6 %, respectively. According to calculations based on data from the Russia Longitudinal Monitoring Survey, the prevalence of obesity among men increased from 8.5 % in 1994 to 16.6 % in 2022, and among women from 21.1 % to 27.5 %, respectively. After 2012, there was no significant increase in obesity prevalence in any of the age groups, with the possible exception of 15–24-year-old men and women aged 65 and older. The data suggests that the obesity epidemic in Russia has stabilized and the increase in the prevalence of obesity in recent years was largely due to the population aging. Also, Rosstat data show an increase in obesity prevalence during the COVID-19 pandemic from 23.0 % in 2019 to 25.0 % in 2021, while the rate remained at the same level (24.9 %) in 2022. In the structure of obesity calculated on the basis of Rosstat data, obesity of the I degree prevails both among men (80.5 %) and women (68.1 %).

   Conclusion. The growing prevalence of obesity in Russia, given the associated risks of morbidity and mortality, raises concerns and requires appropriate public health measures.

   Introduction. In 2021, the results of the first large-scale prospective cohort study were published showing the negative impact of post-diagnosis smoking on the prognosis of non-small cell lung cancer (I-IIIа).

   The purpose of the study is to assess the possible benefits of postdiagnosis smoking cessation of patients with non-small cell lung cancer (NSLC) stage I–IIIa to both the health care system society as a whole.

   Materials and methods. A mathematical model (calculator) has been developed to calculate the economic benefits of smoking cessation among patients with a confirmed diagnosis of NSCLC (I–IIIa). The calculator uses indicators characterizing the postdiagnosis smoking status of patients with stage I–IIIa NSCLC, the probability of disease progression and survival in the groups of those who continue to smoke and those who quit smoking. These data were obtained from the prospective epidemiologic study performed in the department of clinical epidemiology, N. N. Blokhin NMRC of oncology in cooperation with the IARC. The calculator takes into account the average cost of treating patients with late-stage NSCLC (IIIb-IV stage) in 2020–2022, which is calculated based on an analysis of the medical records of patients who were treated in the Department of Medical Cancer Therapy No. 3 of the of the Federal State Budgetary Institution «N. N. Blokhin National Medical Research Center of Oncology» (Head K. K. Laktionov), statistical data on incidence and mortality from NSCLC in Russia, the Gross Domestic Product (GDP) per capita indicator, and the MINEC Forecast of socio-economic development of the Russian Federation for 2023, 2024 and 2025.

   Results. Stopping smoking after diagnosis of NSCLC stage I–IIIa results in cost savings due to a reduced likelihood of relapses and an increased number of patients who avoid relapses when quitting smoking. Taking into account the fact that the average cost of treatment for patients with stage IIIb–IV NSCLC is 4,000,000 rubles, savings on treatment due to a decrease in the likelihood of relapses and as a result of an increase in the number of relapse-free patients who quit smoking amounted to 3,321 million rubles. and 9,251 million rubles, respectively, per year. Thus, the total cost savings on treatment will amount to 12,588 million rubles or slightly more than 2.3 million rubles per patient who quit smoking. The second source of saving is maintaining the economically active potential of some patients diagnosed with stage I–IIIa NSCLC, due to increased progression free survival as a result of smoking cessation аmounts to 3 304 million rubles per year in terms of per capita GDP. If 100 % of patients with stage I–IIIa NLCLC hypothetically quit smoking, the potential budget savings could reach a significantly greater value of 29,480 million rubles per year. The economic benefit to society in the total metric of per capita GDP, obtained as a result of increased survival and possible preservation of labor activity, could exceed 14 billion rubles over a 5-year period.

   Conclusion. Smoking cessation in cancer patients is accompanied not only by clinical benefits, i. e. it reduces mortality and improves survival rates, but also by economic benefits for the healthcare system and the country as a whole.

   Introduction. Sociological surveys are a reliable source of information about the quality of medical care provided. Assessing the subjective opinions of all participants in the treatment and preventive process about the organization of medical care allows for timely adjustments to the volume and quality of medical services provided. The study of subjective assessments of medical personnel about the quality of medical care provided determines its effectiveness and requires additional research.

   The purpose of the study is to study the opinions of medical workers, assess the influence of possible factors on the responses of respondents, in connection with the inclusion of remote blood pressure monitoring in their functional responsibilities.

   Materials and methods. Study was conducted on the basis of two city clinics of St. Petersburg No. 19 and 91. The materials were data from a sociological survey of medical workers who took part in organizing the provision of medical care using remote blood pressure monitoring to patients of the cardiology follow-up group in the period from 2018 to 2022.

   Results. An analysis was carried out of the influence of some factors on the respondents’ answers in connection with the inclusion of remote blood pressure monitoring in their functional responsibilities.

   Conclusion. Data processing showed that, in general, this led to an increase in the satisfaction of medical workers with various aspects of professional activity related to communication processes in the team – improved mutual understanding with colleagues and management and a decrease in the number of conflicts with patients. Regarding factors of labor organization and remuneration, significant resources were noted to determine directions for their solution.

   Introduction. One of the strategies for reducing maternal mortality is to improve the provision of medical care to pregnant women, women in labor and maternity hospitals in need of intensive care. Sufficient provision of anesthesiology and intensive care units of maternity institutions with highly qualified personnel is the most important factor determining the availability and quality of medical care for women.

   The purpose of the study: to analyse the staffing of the anaesthesiology and resuscitation services of obstetric hospitals in the Russian Federation.

   Materials and methods. Based on the data of 83 subjects of the Russian Federation, the indicators of staffing (per 10,000 women of fertile age) with anaesthesiologists-resuscitators (for 2007–2022) and nurses anaesthesiologists (for 2021–2022), staffing levels and compatibility ratios of anaesthesiologist-resuscitators and nurses anaesthesiologists in obstetric hospitals of group II and III (level) (for 2022) in the Russian Federation, federal districts and subjects of the Russian Federation were analysed. Based on data from 29 subjects of the Russian Federation (for 2021), the average age of anaesthesiologists-resuscitators and nurses anaesthesiologists working in obstetric hospitals was analysed.

   Results. In 2007–2022, the number of anaesthesiologists-resuscitators in obstetric hospitals of the Russian Federation increased by 27.2 %, and the availability of anaesthesiologists-resuscitators (per 10,000 women of fertile age) increased by 43.9 %. The number of nurse anaesthesiologists in obstetric hospitals in 2021–2022 increased by 0.8 %, the availability of nurse anaesthetists (per 10,000 women of fertile age) decreased by 0.8 %. In 2022, the staffing level of anaesthesiologists-resuscitators in obstetric hospitals of Group II was 85.6 %, Group III – 86.0 %, and nurses anaesthesiologists – 87.8 % and 88.4%, respectively. The compatibility rate of anaesthesiologists-resuscitators in obstetric hospitals of group II was 1.42, group III – 1.53, and nurse anaesthesiologists – 1.23 and 1.34 respectively (2022). The average age of anaesthesiologists-resuscitators working in obstetric hospitals was 43.3 ± 4.3 years, nurse anaesthesiologists – 42.1 ± 3.9 years (2021).

   Conclusion. In order to eliminate staff shortages, it is necessary to implement measures to attract medical staff in the anaesthesiology and resuscitation services of obstetric institutions, which will decrease the burden on medical staff and prevent maternal deaths.

   Introduction. Depressive disorders have ceased to be only the task of psychiatrists. Depression is detected in patients with a somatic and neurological profile as a reaction to the disease, and may be the cause of the disease. The number of above-mentioned pathologies remains unknown to date. The main task for health care organizers is the need to build an algorithm for the identification, registration and treatment of depressive disorders in patients with combined pathologies. This article discusses depressive disorders in patients with multiple sclerosis.

   The purpose of the study: to study depressive disorders and factors influencing depression in patients with multiple sclerosis.

   Materials and methods. 203 patients with clinically confirmed diagnosis of MS participated. Taking into account the course of the disease, MS patients were distributed: with a remitting (RRS) type of MS course 88.2 % (179 people) and 11.8 % (24 people) with a secondary progressive course (RRS). The average age of the examined patients with remitting course (RRS) ranged from 15 to 63 years, on average 38 ± 10 years. The age of the examined patients with HPV is in the range from 29 to 65 years, on average (46 ± 9.00) years. The majority of patients had a disease duration of less than 20 years, on average 8.23±6.57 years. The average age of onset of the disease is 30.2±10.5 years. The duration of the disease is 9.84 ± 0.73 years, while the level of disability of patients (score in points on the Expanded Disability Status Scale/EDSS) at the time of examination was 2.89 ± 0.16 points. The disability index varied in patients with RRS2.89 ± 0.16 points, in patients with RRS (5.0 ± 0.24) points.

   Results and discussion. 55.7 % (113 people) of MS patients were diagnosed with depression, of which 80.5 % (91 people) and 19.5% (22 people) of patients with a remitting (RRS) course and a secondary progressive course of the disease (RRS). More than 54.8 % (62 people) had mild and moderate depressive manifestations, 39.8 % (45 people) most often had mixed anxiety-depressive disorder, recurrent depressive disorder, then depressive episodes. It was revealed that the development of depression in patients with a remitting course is influenced by: «disease duration» PC p = 0.00333**, «disability level» p = 0.0457* and «personal anxiety» p = 0.0194. In patients with a secondary progressive course, depression is influenced by the following factors: «situational» p = 0.0398* and «personal anxiety» p = 1.740. The social status determined that patients with «MS without depression» who were married were statistically less likely to suffer from depression and maintained their working capacity longer (p < 0.001).

   Conclusion. Depressive disorders are the leading disorders in neurological patients, but their number and severity of symptoms are often ignored by specialists. Therefore, the health authorities are faced with the task of building a clinical and organizational algorithm for the identification of depressive disorders, as well as their timely medical correction.

   Introduction. The health of children and adolescents is a criterion of their body’s relationship with the environment and is formed under the influence of a complex set of social, biological and environmental factors. Educational organizations are the only system of public education that covers the entire child and adolescent population of the country for a long period of time. Physical factors of the intra-school environment affect the physiological processes of the body of schoolchildren and ensure adaptation to physical exertion.

   The purpose of the study: to study and evaluate the physical factors of the educational environment in schools of the Chelyabinsk region in the dynamics of five years and the adaptive potential of students.

   Materials and methods. Statistical, mathematical and instrumental research methods are used in the work. The conditions of physical education classes in 10 schools in the cities of the Chelyabinsk region from 2018–2022 were studied and an assessment of physical performance was carried out in 102 students of grades 8–9. It was found that the largest share was accounted for by objects classified as medium risk and moderate risk in 2020–82.8 %.

   Results. The proportion of educational institutions that do not meet sanitary and hygienic standards in terms of artificial illumination and electromagnetic studies remained high and amounted to 14.2 % and 8.9%, respectively, excess air temperature was detected in 20 % of the studied schools. In 60 % of the schools studied, outdoor sports grounds have not been repaired since they were put into operation.

   Conclusion. 26.7 % of respondents showed satisfactory adaptation to physical exertion, 73.3 % (2.8 times more) of respondents noted the strain of adaptation mechanisms. The number of students with overweight and revealed stress of adaptation mechanisms was 66.7 %, and with a lack of body weight, this figure was 2.1 times less and amounted to 28.5 %. A third (33.3 %) of overweight respondents showed satisfactory adaptation, while underweight students showed 2.2 times higher (71.5 %).

   Introduction. Despite the high level of vaccination, some groups of the population still lack reliable information about vaccines and resources with which to familiarize themselves with it. Social and behavioral changes are a key element of an effective response to COVID-19, such as increasing the level of knowledge of the population through the dissemination of information and educational materials on vaccination of the population against coronavirus infection.

   The purpose of the study: to assess the level of knowledge about COVID-19, behavioral practices, as well as attitudes towards vaccination and other ongoing anti-epidemic measures among the population of the Republic of Tajikistan.

   Materials and methods. The study was conducted by the NGO “Subhi Tandurusti” from February to May 2024. To assess the level of respondents in the Knowledge, Attitudes and Practices survey regarding issues related to COVID-19, a questionnaire survey was conducted using a specially designed questionnaire. The study involved 2,500 respondents from 15 different districts and cities of the republic.

   Results. About 93 % of respondents (n = 2322) correctly answered this question regarding modes of transmission of the virus, indicating a high level of awareness of modes of transmission of COVID-19. Relatively high rates of correct answers were recorded to the question “Is it possible to get sick with COVID-19 several times?” 69.5 % of respondents (n = 1737) answered this question correctly, indicating an understanding that it is possible to get sick with COVID-19 several times. Attitude of respondents regarding the safety and effectiveness of vaccination: 78.3 % of respondents (n = 1957) expressed confidence in its safety, 11.3 % (n = 282) did not know the answer, and 10.4 % (n = 261) did not consider the vaccine safe. 2,430 people (97.20 %) have already received the full course of vaccination against COVID-19, 42 people (1.68 %) have only received the first dose of the vaccine and are planning to receive the second. The most popular source of information about COVID-19 was television programs – 44.0 % of respondents (n = 1101), followed by information materials (25.2 %, n = 631) and the Internet, including websites and social networks (22.8 %, n = 571). At the same time, 75.6 % (n = 1889) of respondents rated information and educational materials about COVID-19 as very useful and reliable. To the question “Have you been tested?”: 639 people (25.6 %) “never” got tested, 588 (23.5 %) “often” and 461 (18.4 %) “always” got tested.

   Conclusion. The results of the study showed that the interviewees had sufficient knowledge about COVID-19, including the transmission of the virus through various routes and clinical symptoms of the disease, as well as the importance of vaccination. Public health initiatives help better protect public health during emergencies such as infectious disease pandemics.