In 2020 we observed a sudden decline in cancer incidence in Russia in comparison with 2019. The age-standardized rates (ASR) per 100,000 population of cancers that were on increase before 2019 dropped abruptly including cancers of the colorectum, prostate, breast, thyroid, kidney, while for those cancers that steadily decreased including cancers of the lung and stomach, the decrease has speeded up.

The difference between predicted and actual number of cases registered in 2020 was 98 142 for all cancers, 24 172 for skin cancer (excluding melanoma), 13202 – for prostate cancer 11 660 – for breast cancer, 9570 – for colorectal cancer, 7235 – for lung cancer, 5450 – for kidney cancer, 3506 for gastric cancer, 2744 for urinary bladder cancer, 2436 – thyroid cancer and 2080 for melanoma.

The observed decrease in cancer incidence in 2020 reflects the decrease in the detection rate of cancer. Following arguments might explain this decrease. First the individuals with complains or symptoms who in normal situation would seek medical advice might have barriers for consulting doctor due to isolation and lockdowns. For the same reason the coverage of the population by the check-up programs temporarily decreased including screening for breast, cervix, colorectal and prostate cancer. Regrettably there are no data on the population coverage of these screening programs either before (in 2019) or at the time of COVID epidemic (in 2020).

For most of these tumors the effective screening tests are available that if applied correctly with quality control contribute to early diagnosis and consequently to the improvement of survival and decrease in mortality.

The decrease in the detection rate of cancer in 2020 and 2021 (still to be seen) will result in the shift of the stage of cancer at diagnosis from early to late stages. The proportion of cancer patients diagnosed at the stages III–IV will increase and will be followed by increase in mortality from cancer.

The decrease in cancer detection rate is observed in many counties. The Covid‑19 pandemic affected cancer control in Europe. In one third of the countries in Europe the pressure on the health system created by the Covid –19 pandemic caused interruptions in cancer care.

To handle effectively the problem of the underdiagnosis of cancer during the Covid‑19 pandemic we have to address population using all available ways of communication and explain that the decrease in detection rate of cancer will be followed by shifting the stage of detected cancer from early to late stages and this will affect its curability. People should be advised to see doctor immediately for any health problems. To make this advice effective the accessibility of cancer diagnostic and treatment facilities need to return to pre-pandemic level.

Screening programs should be restored. However, they need to be adjusted to the WHO guidelines and the existing international experience. WHO guidelines recommend screening for colorectal, breast and cervical cancer. Cervical cancer screening – preferably using HPV testing that is much more sensitive than cytological testing and could be carried out twice in the life at age 35 and 45 years.

The evidence-based cancer control program will not only help us to overcome the consequences of the pandemic and returning to the pre-pandemic state but also will promote further decline of cancer mortality.

Introduction. Aggressive behavior of children and adolescents in the educational environment should be assessed differentially depending on the nature of its manifestation and the age of the student. Extreme variants of aggression, expressed in attacks on educational institutions, are multifactorial in nature and combine auto- and hetero-aggressive tendencies.

Goal. Identifying medical and psychological indicators of vulnerabilities in adolescents, warning of the possibility of their auto- and hetero-aggressive behavior, also in the educational environment.

Material and methods. Qualitative and descriptive analysis of the empirical material of complex forensic psychological and psychiatric examinations of minors with suicidal and hetero-aggressive behavior.

Results. Behavioral indicators and typological psychological features inherent in this category of adolescents are described. The order of work of specialists (teachers, school and clinical psychologists, social educators, psychiatrists) with adolescents displaying these behaviors is presented. Particular attention is paid to the clinical manifestations of mental disorders that can be found in such adolescents.

Conclusions. Prevention of auto- and hetero-aggressive behavior of adolescents in the educational environment, starting with the fixation of described behavioral indicators, requires the consistent involvement of various specialists in work with adolescents and their interdisciplinary and interdepartmental interaction.

In order to study the availability and structure of the suicidological service of Russia, an analysis of data from 76 regions received in response to the request of the Government of the Russian Federation No. 2098-r dated September 18, 2019 for the approval of a set of measures to improve the system of suicide prevention of minors, as well as data from field events of employees of the National Medical Research Center for Psychiatry and Drug Addiction was carried out V. P. Serbsky in 44 regions of the Russian Federation in 2019, the majority of regions report on regional suicidological services to the population, represented mainly by “Helplines” (77%), offices of a suicidologist in the HDP (46%). The full composition of the links of the suicidological service is only in Moscow, Bashkortostan, Krasnodar, Stavropol, Trans-Baikal Territories, Tyumen, Sverdlovsk regions. Standardized accounting and registration of suicidal attempts only in certain regions (Tyumen Region, Stavropol Territory). A system for diagnosing suicidal behavior in the general medical network and educational organizations has not been developed. There is no algorithm for interdepartmental interaction in the management of persons with suicidal behavior. Proposals have been made to improve the work of the suicidological service at the federal and regional levels.

Reducing suicide-related mortality rate is one of the tasks outlined within the Russian national demographic policy. The purpose of this work is to create a regional model for monitoring intentional self-harm with non-lethal outcome (attempted suicide) based on principles of standardization and personification subject to preventive approaches. The methods employed through the respective work included summarizing of experience, project development, experiment (project implementation), object following method (monitoring), statistical analysis of the obtained data as well as the efficiency analysis for the project, and automation. Main outcomes: 1) inclusion and exclusion criteria specified for the monitoring system; 2) list of registered indicators specified as well as indicators defined, which are descriptive of the population’s suicidality rate; 3) subjects for the monitoring system have been identified; 4) monitoring processes have been identified; 5) rate of the completed suicides and intentional self-harm cases in the region has been detected – 1:1,8; 6) the availability of primary assistance for people registered with intentional self-harm was 78,6% for the adult population and 79,7% – for the child population. In conclusion, there have been potential ways for suicide prevention system identified in terms of implementing the principles of predictive, preventive and personalized medicine.

The purpose of this article is to form the key principles for organizing comprehensive care for people with mental disabilities. The basis for the development of principles was the experience of implementing the public project “Mental Health” in the Volga Federal District. Based on the experience, the main tasks when including the region in the project will be the organization of continuous support from an early age and throughout life, the organization of interdepartmental interaction, the creation of opportunities for the realization of medical, educational, professional, social and other needs of people with mental disabilities. At the same time, the development and approval at the regional level of a road map, which will identify activities, participants in the assistance program, responsible departments and institutions, as well as deadlines, is of particular importance as one of the main stages in the implementation of comprehensive assistance. Using the principles described in the article in its work, the region can quite effectively create a system of comprehensive assistance to people with mental disabilities, having a minimal backlog in this area.

The article contains detailed statistical characteristics of the suicidal behavior of minors in Altai Krai over the past three years. It describes the experience of organizational and methodical work for the prevention and rehabilitation of children and adolescents with suicidal behavior. The gradual formation assistance to a suicide of the child population in the region is also reflected.